GENETIC STUDIES ON THE ISONIAZID RESISTANCE-SYSTEM OFMYCOBACTERIUM TUBERCULOSISVAR.HOMINIS
نویسندگان
چکیده
منابع مشابه
a study on construction of iranian life tables: the case study of modified brass logit system
چکیده ندارد.
15 صفحه اولImpact of Isoniazid Resistance-Conferring Mutations on the Clinical Presentation of Isoniazid Monoresistant Tuberculosis
BACKGROUND Specific isoniazid (INH) resistance conferring mutations have been shown to impact the likelihood of tuberculosis (TB) transmission. However, their role in the clinical presentation and outcomes of TB has not been evaluated. METHODS We included all cases of culture-confirmed, INH monoresistant tuberculosis reported to the San Francisco Department of Public Health Tuberculosis Contr...
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Los autores han informado previamente, que en ratollcillos infectados por via intravenosa con M. leprae murium, y tratados con isoniazid continuamente por 180 dias, hubo una supresion casi total en I~ multiplicacion de los microorganismos. Ahora se ha descubierto, sinembargo, que si el tratamiento se continua indefinidamente estos ani males muer en antes de un ano con tantos bacilos en los orga...
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NIQUE opportunities for the study of mutations, both spontaneous and U induced, have been offered by what we may call the " phage-resistance system '? of bacterial changes from sensitivity to resistance to bacteriophages. In studying this system it is easy to work with large numbers of bacteria (1 x 108 per Petri dish) ; and if sufficient quantities of phage are added, all sensitive bacteria wi...
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The continuing rise in tuberculosis incidence and the problem of drug resistance strains have prompted the research on new drug candidates and the mechanism of drug resistance. Molecular docking and molecular dynamics simulation (MD) were performed to study the binding of isoniazid onto the active site of Mycobacterium tuberculosis enoyl-acyl carrier protein reductase (InhA) in an attempt to ad...
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ژورنال
عنوان ژورنال: Japanese Journal of Microbiology
سال: 1959
ISSN: 0021-5139
DOI: 10.1111/j.1348-0421.1959.tb00107.x